Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | DPYD | Q12882 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL4487821 | 0.75 | KDM3B (0.62) | GAADPYDALDH1A1LMNAMAPT | |
| SCHEMBL119748 | 0.73 | GAA (0.48) | GAADPYDALDH1A1LMNAMAPT | |
| SCHEMBL190958 | 0.71 | GAA (0.50) | GAADPYDALDH1A1LMNAMAPT | |
| SCHEMBL6524027 | 0.71 | GAA (0.50) | GAADPYDALDH1A1LMNAMAPT | |
| SCHEMBL1210894 | 0.71 | GAA (0.50) | GAADPYDALDH1A1LMNAMAPT | |
| SCHEMBL891086 | 0.71 | GAA (0.45) | GAADPYDALDH1A1LMNAMAPT | |
| Dimethylamine SCHEMBL1524840 | 0.71 | KDM3B (0.56) | GAADPYDALDH1A1LMNAMAPT | |
| SCHEMBL26185882 | 0.71 | DPYD (0.50) | GAADPYDALDH1A1LMNAMAPT | |
| SCHEMBL8775721 | 0.69 | LMNA (0.48) | GAADPYDALDH1A1LMNAMAPT | |
| SCHEMBL16703602 | 0.69 | GAA (0.48) | GAADPYDALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105056226-A | Compositions and methods for the treatment of infections and tumors | UNIV EMORY | 2015-11-18 | — | — | CN | disclosed |
| CN-103536915-A | Compositions and methods for the treatment of infections and tumors | UNIV EMORY | 2014-01-29 | — | — | CN | disclosed |