SCHEMBL891086

SCHEMBL891086

C=C(C(=O)O)c1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
KDM3B Q7LBC6 1/20 0.43
LMNA P02545 3/20 0.42
DPYD Q12882 4/20 0.41
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 2/20 0.41
ATAD2 Q6PL18 1/20 0.41
CYP19A1 P11511 1/20 0.41
TSHR P16473 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41
HTT P42858 1/20 0.41
HBB P68871 1/20 0.41
PMP22 Q01453 1/20 0.41
CYP1A2 P05177 1/20 0.36
CTSL P07711 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119748 0.80 GAA (0.48) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL127493 0.79 KDM3B (0.64) GAAKDM3BLMNADPYDALDH1A1
Water SCHEMBL4487821 0.78 KDM3B (0.62) GAAKDM3BLMNADPYDALDH1A1
Hydrochloric Acid SCHEMBL11439523 0.78 KDM3B (0.62) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL8775721 0.76 LMNA (0.48) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL65890 0.76 GAA (0.48) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL1052427 0.76 GAA (0.48) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL9220471 0.76 GAA (0.48) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL933035 0.76 DPYD (0.48) GAAKDM3BLMNADPYDALDH1A1
SCHEMBL190958 0.74 GAA (0.50) GAAKDM3BLMNADPYDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230407419-A1 Rapid Diagnostic Test for LAMP NEW ENGLAND BIOLABS, INC. (US) 2023-12-21 US disclosed
US-11732315-B2 Rapid diagnostic test for lamp NEW ENGLAND BIOLABS, INC. (US) 2023-08-22 US disclosed
US-20230048863-A1 Rapid Diagnostic Test for LAMP NEW ENGLAND BIOLABS, INC. (US) 2023-02-16 US disclosed
US-20230022745-A1 Methods for Labeling a Population of RNA Molecules NEW ENGLAND BIOLABS, INC. (US) 2023-01-26 US disclosed
EP-4118233-A1 A RAPID DIAGNOSTIC TEST FOR LAMP New England Biolabs, Inc. (US) 2023-01-18 EP disclosed
EP-4110945-A2 A RAPID DIAGNOSTIC TEST FOR LAMP New England Biolabs, Inc. (US) 2023-01-04 EP disclosed
US-11525166-B2 Rapid diagnostic test for LAMP NEW ENGLAND BIOLABS, INC. (US) 2022-12-13 US disclosed
US-11479766-B2 Methods for labeling a population of RNA molecules NEW ENGLAND BIOLABS, INC. (US) 2022-10-25 US disclosed
US-20220213564-A1 Rapid Diagnostic Test for LAMP NEW ENGLAND BIOLABS, INC. (US) 2022-07-07 US disclosed
US-20220195424-A1 Chemical Capping for Template Switching NEW ENGLAND BIOLABS, INC. (US) 2022-06-23 US disclosed
US-11345970-B2 Rapid diagnostic test for LAMP NEW ENGLAND BIOLABS, INC. (US) 2022-05-31 US disclosed
WO-2022040443-A2 A RAPID DIAGNOSTIC TEST FOR LAMP NEW ENGLAND BIOLABS, INC. (US) 2022-02-24 WO disclosed
US-20210404024-A1 Rapid Diagnostic Test for LAMP NEW ENGLAND BIOLABS, INC. (US) 2021-12-30 US disclosed
WO-2021183921-A1 A RAPID DIAGNOSTIC TEST FOR LAMP NEW ENGLAND BIOLABS, INC. (US) 2021-09-16 WO disclosed
WO-2020231697-A1 CHEMICAL CAPPING FOR TEMPLATE SWITCHING NEW ENGLAND BIOLABS, INC. (US) 2020-11-19 WO disclosed
US-20180195061-A1 Methods for Labeling a Population of RNA Molecules NEW ENGLAND BIOLABS, INC. (US) 2018-07-12 US disclosed
EP-2272856-B1 SEQUENCE-SPECIFIC NUCLEIC ACID PURIFICATION METHOD MANNER JAPAN ADV INST SCIENCE & TECH (JP) 2015-11-04 EP disclosed
US-9157885-B2 Method of electrochemically detecting target substance, method of electrochemically detecting analyte, test chip, and detection set SYSMEX CORPORATION (JP) 2015-10-13 US disclosed
US-20120080324-A1 METHOD OF ELECTROCHEMICALLY DETECTING TARGET SUBSTANCE, METHOD OF ELECTROCHEMICALLY DETECTING ANALYTE, TEST CHIP, AND DETECTION SET SYSMEX CORPORATION (JP) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195061-A1 Methods for Labeling a Population of RNA Molecules RNGTT, RNMT, MTAP GAA 465/4885KDM3B 1477/4885LMNA 2087/4885
US-11479766-B2 Methods for labeling a population of RNA molecules RNGTT, RNMT, MTAP GAA 465/4885KDM3B 1477/4885LMNA 2087/4885
US-20230022745-A1 Methods for Labeling a Population of RNA Molecules RNGTT, RNMT, MTAP GAA 465/4885KDM3B 1477/4885LMNA 2087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.