Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | SDHB | P21912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950350 | 0.87 | PPARG (0.35) | POLBMAPTPPARGPPARAPPARD | |
| SCHEMBL28947564 | 0.86 | RORC (0.39) | POLBMAPTPPARGPPARAPPARD | |
| SCHEMBL28807374 | 0.82 | RORC (0.39) | PPARGPPARAPPARDRORCKCNN4 | |
| SCHEMBL27950250 | 0.80 | RORC (0.36) | POLBMAPTPPARGCYP3A4CYP2C9 | |
| SCHEMBL27950235 | 0.78 | RXRA (0.34) | PPARGPPARAPPARD | |
| SCHEMBL27936033 | 0.78 | RORC (0.41) | POLBMAPTPPARGPPARAPPARD | |
| SCHEMBL27950241 | 0.77 | MAPT (0.35) | MAPTPPARGPPARARORCLMNA | |
| SCHEMBL28806427 | 0.77 | MEN1 (0.38) | POLBPPARGPPARAPPARDCYP3A4 | |
| SCHEMBL27936023 | 0.75 | RORC (0.40) | PPARGPPARAPPARDRORCACLY | |
| SCHEMBL27909997 | 0.75 | PPARG (0.35) | POLBPPARGPPARAPPARDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554006-A | Use of indole derivatives as nurr-1 activators for the application thereof as a medicament for the treatment of parkinson's disease | FOURNIER LAB SA | 2014-02-05 | — | — | CN | disclosed |