Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 5/20 | 0.34 |
| ▸ | PLG | P00747 | 4/20 | 0.34 |
| ▸ | PLAT | P00750 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28809392 | 1.00 | CTSL (0.35) | CTSLDGAT1PLAUPLGPLAT | |
| SCHEMBL31357614 | 0.89 | PLAU (0.36) | DGAT1PLAUPLGPLAT | |
| SCHEMBL31357691 | 0.89 | PLAU (0.36) | DGAT1PLAUPLGPLAT | |
| SCHEMBL23595147 | 0.89 | PLAU (0.36) | DGAT1PLAUPLGPLAT | |
| SCHEMBL31357651 | 0.88 | CNR2 (0.37) | CTSLDGAT1CTSSCTSKCTSB | |
| SCHEMBL28809474 | 0.88 | CNR2 (0.37) | CTSLDGAT1CTSSCTSKCTSB | |
| SCHEMBL23582452 | 0.86 | SHMT1 (0.40) | PLAUPLGPLATSHMT1SHMT2 | |
| SCHEMBL23582711 | 0.85 | DGAT1 (0.37) | DGAT1PLAUPLGPLATCCNT1 | |
| SCHEMBL31357628 | 0.85 | DGAT1 (0.37) | DGAT1PLAUPLGPLATCCNT1 | |
| SCHEMBL31357685 | 0.84 | EGFR (0.35) | DGAT1EGFRAURKBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114846013-B | Novel aminoaryl derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2024-12-20 | — | — | CN | disclosed |