Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.43 |
| ▸ | LPL | P06858 | 4/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25427311 | 0.89 | DGAT1 (0.41) | LIPGLPLDGAT1HIF1AAAK1 | |
| SCHEMBL4045906 | 0.87 | ELANE (0.41) | LIPGLPLDGAT1HIF1AELANE | |
| SCHEMBL29913985 | 0.82 | ACHE (0.50) | LIPGLPLHIF1AROCK1ELANE | |
| SCHEMBL3451076 | 0.80 | CYP3A4 (0.50) | LIPGLPLHIF1AROCK1CA1 | |
| SCHEMBL28516345 | 0.80 | LIPG (0.41) | LIPGLPLDGAT1HIF1AAAK1 | |
| SCHEMBL1318656 | 0.80 | ELANE (0.42) | LIPGLPLDGAT1HIF1AAAK1 | |
| SCHEMBL5761327 | 0.79 | MEN1 (0.54) | LIPGLPLHIF1AROCK1CA1 | |
| SCHEMBL28469721 | 0.79 | AAK1 (0.40) | LIPGLPLDGAT1HIF1AAAK1 | |
| SCHEMBL28521280 | 0.79 | ACHE (0.44) | LIPGLPLHIF1A | |
| SCHEMBL23582562 | 0.78 | PPARA (0.52) | LIPGLPLDGAT1HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114846013-A | Novel aminoaryl derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2022-08-02 | — | — | CN | disclosed |