Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507014 | 0.81 | NPC1 (0.46) | ELANERAB9ANPC1TP53HPGD | |
| SCHEMBL1755255 | 0.80 | PLA2G7 (0.47) | ELANERAB9ANPC1TP53HPGD | |
| SCHEMBL30883375 | 0.80 | S100A4 (0.48) | RAB9ANPC1TP53HPGDTSHR | |
| SCHEMBL16548116 | 0.80 | ELANE (0.50) | ELANERAB9ANPC1TP53HPGD | |
| SCHEMBL17268322 | 0.77 | HSD11B1 (0.50) | ELANERAB9ANPC1TP53HPGD | |
| SCHEMBL28478846 | 0.77 | ELANE (0.47) | ELANERAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL942740 | 0.77 | CYP2A6 (0.50) | RAB9ANPC1TP53HPGDTDP1 | |
| SCHEMBL31345280 | 0.77 | GPR3 (0.45) | TP53L3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL15259434 | 0.76 | ELANE (0.50) | ELANERAB9ANPC1TP53HPGD | |
| SCHEMBL28552155 | 0.76 | ELANE (0.50) | ELANERAB9ANPC1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890987-A | Thiophenol-thiophene ligand and preparation method thereof, olefin polymerization catalyst and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-12 | — | — | CN | disclosed |