SCHEMBL288097

SCHEMBL288097

O=C(O)C(Cc1ccccc1)N(F)F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
ALPI P09923 1/20 0.52
PKM P14618 1/20 0.52
PTGS1 P23219 1/20 0.52
XIAP P98170 1/20 0.52
SLC7A5 Q01650 1/20 0.52
CPA1 P15085 3/20 0.48
CPA3 P15088 3/20 0.48
FOLH1 Q04609 1/20 0.48
CPB1 P15086 1/20 0.48
CPB2 Q96IY4 1/20 0.48
SRR Q9GZT4 2/20 0.47
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MDM2 Q00987 1/20 0.46
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475786 1.00 CYP1A2 (0.55) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL20494781 0.85 SLC7A5 (0.55) SLC7A5FOLH1
SCHEMBL27878043 0.85 ALPI (0.53) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL25212796 0.85 CYP1A2 (0.52) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL27878042 0.85 ALPI (0.53) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL25212797 0.85 CYP1A2 (0.52) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL29462781 0.83 SOAT1 (0.41) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL23270969 0.82 CYP1A2 (0.48) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL6006043 0.82 CYP1A2 (0.48) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL23270961 0.82 CYP1A2 (0.48) CYP1A2ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119715853-A Semi-quantitative assessment method for substitution degree of non-protein amino acid 遵义医科大学 2025-03-28 CN claimed
EP-3347369-B1 NOVEL COMPOUNDS WITH DUAL ACTIVITY YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) 2024-04-17 EP claimed
US-8883721-B2 Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof MCGILL UNIVERSITY (CA) 2014-11-11 US claimed
WO-2013142229-A1 DESIGNING NOVEL PEPTIDES FOR INDUCING FIBRONECTIN MATRIX ASSEMBLY PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-09-26 WO claimed
US-20120135918-A1 METHODS OF INHIBITING THE GHRELIN/GROWTH HORMONE SECRETATOGUE RECEPTOR PATHWAY AND USES THEREOF MCGILL UNIVERSITY (CA) 2012-05-31 US claimed
WO-2011126882-A2 THERAPEUTIC PEPTIDES AND THEIR DERIVATIVES AND THERAPEUTIC USES THEREOF AMERICAN TYPE CULTURE COLLECTION (US) 2011-10-13 WO claimed
WO-2010132580-A2 METHODS OF INHIBITING THE GHRELIN/GROWTH HORMONE SECRETATOGUE RECEPTOR PATHWAY AND USES THEREOF THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2010-11-18 WO claimed
US-20060148714-A1 Therapeutic peptide-based constructs LITTLE ROGER G II 2006-07-06 US claimed
US-6964948-B2 Therapeutic peptide-based constructs derived from Domain II of bactericidal/permeability-increasing protein XOMA TECHNOLOGY LTD. (BM) 2005-11-15 US claimed
US-6906037-B2 Therapeutic peptide-based constructs XOMA TECHNOLOGY LTD. (BM) 2005-06-14 US claimed
US-20040048793-A1 Therapeutic peptide-based constructs LITTLE ROGER G (US) 2004-03-11 US claimed
US-20030144195-A1 Therapeutic peptide-based constructs LITTLE ROGER G (US) 2003-07-31 US claimed
US-6515104-B1 8-15 amino acid moieties having heparin neutralization and binding and inhibiting endothelial cell proliferation and/or angiogenesis; diagnotic applications XOMA TECHNOLOGY LTD. (BM) 2003-02-04 US claimed
US-6423825-B1 OCTA-, NONA-, DECA- OR POLYPEPTIDE; HEPARIN BINDING AND NEUTRALIZATION; ANTIPROLIFERATIVE AGENTS OF ENDOTHELIAL CELLS; ANGIOGENESIS INHIBITORS XOMA TECHNOLOGY LTD. (BM) 2002-07-23 US claimed
EP-1196440-A2 THERAPEUTIC PEPTIDES DERIVED FROM SUBSEQUENCES OF BPI XOMA Technology Ltd. (US) 2002-04-17 EP claimed
US-6355616-B1 FUNGICIDE OLIGOPEOTIDES XOMA (US) TECHNOLOGY LTD. 2002-03-12 US claimed
WO-2001000671-A1 DERIVATIVE COMPOUNDS XOMA TECHNOLOGY LTD. (US) 2001-01-04 WO claimed
WO-2001000655-A2 THERAPEUTIC PEPTIDES DERIVED FROM SUBSEQUENCES OF BPI XOMA TECHNOLOGY LTD. (US) 2001-01-04 WO claimed
EP-4748438-A2 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT FOR TYPE 2 DIABETES Cedars-Sinai Medical Center (US) 2026-05-27 EP disclosed
WO-2000011022-A1 ANTI-CANCER COMPOUNDS AND METHODS RELATED THERETO STEWART JOHN M (US) 2000-03-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120135918-A1 METHODS OF INHIBITING THE GHRELIN/GROWTH HORMONE SECRETATOGUE RECEPTOR PATHWAY AND USES THEREOF GHSR, GIPR, GHRHR CYP1A2 3570/4885ALPI 2152/4885PKM 4294/4885
US-20060148714-A1 Therapeutic peptide-based constructs SPPL2B, LNPEP, VIP CYP1A2 4885/4885ALPI 1779/4885PKM 3769/4885
US-20030144195-A1 Therapeutic peptide-based constructs LNPEP, SPPL2B, ENPEP CYP1A2 4883/4885ALPI 1454/4885PKM 3804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.