Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2245496 | 0.72 | HTR6 (0.56) | TSHRMAPK1TDP1RNASEH1HAO1 | |
| SCHEMBL27944129 | 0.69 | CA2 (0.48) | TSHRMAPK1TDP1RNASEH1HAO1 | |
| SCHEMBL27944128 | 0.67 | RNASEH1 (0.41) | TSHRMAPK1TDP1RNASEH1HAO1 | |
| SCHEMBL11629539 | 0.66 | MEN1 (0.56) | TSHRMAPK1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL3298586 | 0.66 | IDO1 (0.64) | HAO1SLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11629535 | 0.65 | IDO1 (0.56) | TSHRMAPK1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL11361475 | 0.65 | HAO1 (0.58) | TSHRTDP1RNASEH1HAO1TBXA2R | |
| SCHEMBL366289 | 0.65 | HAO1 (0.67) | TSHRRNASEH1HAO1TBXA2RPTGER1 | |
| SCHEMBL1206803 | 0.64 | FFAR1 (0.69) | FFAR1PDPK1FFAR4PYGLTRPV1 | |
| SCHEMBL24258002 | 0.64 | TSHR (0.74) | TSHRMAPK1TDP1RNASEH1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102617487-B | Multi-substituted pyrimidinones compounds as well as preparation method and application thereof | UNIV BEIJING TECHNOLOGY | 2014-04-02 | — | — | CN | disclosed |