Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984873 | 0.78 | KCNJ1 (0.67) | KCNJ1KCNH2LTA4HPOLBMAPT | |
| SCHEMBL31734574 | 0.74 | HPGDS (0.51) | KCNJ1KCNH2HPGDSLTA4HRAB9A | |
| SCHEMBL722557 | 0.72 | LTA4H (0.64) | KCNJ1KCNH2HPGDSLTA4HHDAC4 | |
| SCHEMBL29033804 | 0.72 | KCNJ1 (0.44) | KCNJ1KCNH2HPGDSLTA4HPOLB | |
| SCHEMBL23833623 | 0.72 | HPGDS (0.53) | KCNJ1KCNH2HPGDSLTA4HHDAC4 | |
| SCHEMBL30094483 | 0.72 | HPGDS (0.53) | KCNJ1KCNH2HPGDSLTA4HHDAC4 | |
| SCHEMBL3043645 | 0.71 | LTA4H (0.63) | KCNJ1KCNH2LTA4HMAPTRAB9A | |
| SCHEMBL6354500 | 0.71 | MAPT (0.47) | KCNJ1KCNH2LTA4HPOLBMAPT | |
| SCHEMBL27218089 | 0.71 | MAPT (0.55) | KCNJ1KCNH2MAPTLMNAALDH1A1 | |
| SCHEMBL1830727 | 0.71 | NPC1 (0.55) | KCNJ1KCNH2LTA4HPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901280-B | MrgprX2 antagonists and uses thereof | 德米拉公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-114901280-A | MrgprX2 antagonists and uses thereof | 德米拉公司 | 2022-08-12 | — | — | CN | disclosed |