Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27960630 | 0.85 | APEX1 (0.41) | KMT2AFLT1FLT4KDR | |
| SCHEMBL27960685 | 0.78 | KDM4E (0.42) | FLT1FLT4KDRL3MBTL1ALDH1A1 | |
| SCHEMBL11824718 | 0.74 | ALDH1A1 (0.51) | MEN1KMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL14676570 | 0.73 | MMP2 (0.52) | PPARAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL28811650 | 0.72 | THRB (0.48) | MEN1KMT2AF2PRSS1PRSS2 | |
| SCHEMBL27880968 | 0.72 | KMT2A (0.53) | MEN1KMT2AMAPTCYP3A4NPC1 | |
| SCHEMBL10596843 | 0.71 | PPARA (0.44) | MEN1KMT2AENPP3ENPP1PPARA | |
| SCHEMBL29179755 | 0.70 | NPC1 (0.58) | MEN1KMT2AMAPTCYP3A4NPC1 | |
| SCHEMBL3755534 | 0.69 | POLB (0.56) | MEN1KMT2APPARAMAPTCYP1A2 | |
| SCHEMBL15458759 | 0.68 | NPC1 (0.47) | MEN1KMT2AENPP3ENPP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103857655-B | Compounds for inhibiting 11 beta-hydroxysteroid dehydrogenase 1 and pharmaceutical compositions comprising the same | HYUNDAI PHARM Co.,Ltd. (KR) | 2016-03-30 | — | — | CN | disclosed |
| CN-103857655-A | Compounds for inhibiting 11 beta-hydroxysteroid dehydrogenase 1 and pharmaceutical compositions comprising the same | HYUNDAI PHARM CO LTD | 2014-06-11 | — | — | CN | disclosed |