Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29175545 | 0.84 | UCHL1 (0.34) | UCHL1DGAT1F11 | |
| SCHEMBL28811745 | 0.81 | UCHL1 (0.34) | UCHL1ICAM1SELEDGAT1F11 | |
| SCHEMBL29020404 | 0.80 | NFE2L2 (0.35) | UCHL1F11 | |
| SCHEMBL28950774 | 0.78 | DYRK1A (0.37) | UCHL1CCNCCDK8DGAT1F11 | |
| SCHEMBL28839065 | 0.78 | F2 (0.31) | UCHL1F11 | |
| SCHEMBL28811781 | 0.78 | UCHL1 (0.36) | UCHL1DGAT1 | |
| SCHEMBL28438600 | 0.76 | UCHL1 (0.32) | UCHL1 | |
| SCHEMBL24667027 | 0.74 | UCHL1 (0.35) | UCHL1 | |
| SCHEMBL29977339 | 0.74 | UCHL1 (0.35) | UCHL1 | |
| SCHEMBL28607887 | 0.73 | UCHL1 (0.41) | UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853730-B | Compounds used as HPK1 kinase inhibitor, preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-114853730-A | Compound used as HPK1 kinase inhibitor and preparation method and application thereof | 中国药科大学 | 2022-08-05 | — | — | CN | disclosed |