Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 3/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NNMT | P40261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843434 | 0.87 | DGAT1 (0.34) | UCHL1DGAT1LIPEMAPTKMT2A | |
| SCHEMBL28811788 | 0.87 | DGAT1 (0.34) | UCHL1DGAT1LIPEMAPTKMT2A | |
| SCHEMBL28811387 | 0.78 | UCHL1 (0.35) | UCHL1DGAT1 | |
| SCHEMBL28393250 | 0.76 | UCHL1 (0.35) | UCHL1DGAT1LIPEKMT2A | |
| SCHEMBL29165511 | 0.74 | ROCK2 (0.37) | UCHL1DGAT1LIPE | |
| SCHEMBL28811820 | 0.74 | NNMT (0.38) | UCHL1DGAT1LIPESIRT6NNMT | |
| SCHEMBL14745971 | 0.71 | UCHL1 (0.33) | UCHL1DGAT1LIPEKMT2A | |
| SCHEMBL29020404 | 0.71 | NFE2L2 (0.35) | UCHL1LIPEKMT2A | |
| SCHEMBL28811379 | 0.71 | PDGFRB (0.40) | DGAT1 | |
| SCHEMBL28811732 | 0.71 | DGAT1 (0.32) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853730-B | Compounds used as HPK1 kinase inhibitor, preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-114853730-A | Compound used as HPK1 kinase inhibitor and preparation method and application thereof | 中国药科大学 | 2022-08-05 | — | — | CN | disclosed |