SCHEMBL2881153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10095740	0.92	GRIK2 (0.56)	GRIK2GRIK1KDM4EPARP10PARP2
	SCHEMBL2876698	0.91	PARP10 (0.47)	GRIK2GRIK1KDM4EMAPK1ALDH1A1
	SCHEMBL980280	0.90	GRIK2 (0.48)	GRIK2GRIK1KDM4EMAPK1HTT
	SCHEMBL2879121	0.89	PARP10 (0.38)	GRIK2GRIK1KDM4EMAPK1ALDH1A1
	SCHEMBL10095480	0.89	PARP1 (0.47)	GRIK2GRIK1KDM4EMAPK1HTT
	SCHEMBL2881346	0.88	SLC6A2 (0.37)	KDM4EALDH1A1PARP10PARP2MEN1
	SCHEMBL10095252	0.88	GRIK2 (0.60)	GRIK2GRIK1KDM4EMAPK1HTT
	SCHEMBL10095556	0.88	GRIK2 (0.46)	GRIK2GRIK1KDM4EMAPK1HTT
	SCHEMBL10095352	0.88	GRIK2 (0.48)	GRIK2GRIK1KDM4EMAPK1HTT
	SCHEMBL10095298	0.88	GRIK2 (0.46)	GRIK2GRIK1KDM4EMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.