SCHEMBL2881346

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2879121	0.89	PARP10 (0.38)	PARP15PARP10PARP2KDM4EMEN1
	SCHEMBL2881153	0.88	GRIK2 (0.47)	PARP15PARP10PARP2KDM4EMEN1
	SCHEMBL2876698	0.87	PARP10 (0.47)	PARP15PARP10PARP2KDM4EMEN1
	SCHEMBL982387	0.87	TRPA1 (0.39)	SCN5ASCN9ATRPA1KDM4EMEN1
	SCHEMBL2878941	0.85	ALDH1A1 (0.40)	PARP15PARP10PARP2KDM4EMEN1
	SCHEMBL10096208	0.85	PFKFB1 (0.41)	MEN1KMT2ACYP1A2
	SCHEMBL10096182	0.84	PFKFB2 (0.41)	KDM4EKMT2APTGER4
	SCHEMBL10096212	0.84	PFKFB2 (0.44)	KDM4EMEN1ALDH1A1KMT2A
	SCHEMBL10096211	0.84	PFKFB2 (0.41)	ABL1KMT2APTGER4
	SCHEMBL10095288	0.83	GRIK2 (0.49)	SCN5ASCN9ATRPA1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.