Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727379 | 0.82 | GPR35 (0.42) | POLBRECQLGPR35ABCC1MAPT | |
| SCHEMBL8304526 | 0.78 | POLB (0.52) | POLBRECQLGPR35ABCC1MAPT | |
| SCHEMBL3130253 | 0.77 | GPR35 (0.43) | POLBRECQLGPR35ALDH1A1LMNA | |
| SCHEMBL9278011 | 0.77 | KDM4E (0.48) | MAPTALDH1A1L3MBTL1HPGDKDM4E | |
| SCHEMBL3116158 | 0.75 | ALDH1A1 (0.44) | POLBRECQLGPR35MAPTALDH1A1 | |
| SCHEMBL1498222 | 0.75 | GSK3B (0.44) | GPR35ALDH1A1KMT2ADAO | |
| SCHEMBL8104317 | 0.74 | MAPK1 (0.55) | MAPTALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL3497284 | 0.73 | ALDH1A1 (0.61) | POLBRECQLABCC1MAPTALDH1A1 | |
| SCHEMBL9886887 | 0.72 | ALDH1A1 (0.52) | POLBMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL16213064 | 0.72 | EED (0.47) | POLBRECQLGPR35ABCC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009847-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, METHOD FOR THE PRODUCTION THEREOF, AND USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-28 | — | — | WO | disclosed |
| EP-2147919-A1 | Heterocyclic substituted amides, method for their manufacture and their use as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2010-01-27 | — | — | EP | disclosed |
| EP-1016664-B1 | FUSED THIOPHENE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6455521-B1 | PSYCHOLOGICAL DISORDERS; SIDE EFFECT REDUCTION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-09-24 | — | — | US | disclosed |
| US-20020042411-A1 | Condensed thiophene compounds and pharmaceutical use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2002-04-11 | — | — | US | disclosed |
| US-6271225-B1 | PSYCHOLOGICAL DISORDERS | WELFIDE CORPORATION (JP) | 2001-08-07 | — | — | US | disclosed |
| CN-1268949-A | Fused thiophene compounds and medical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2000-10-04 | — | — | CN | disclosed |
| EP-1016664-A1 | FUSED THIOPHENE COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-07-05 | — | — | EP | disclosed |
| EP-0797578-B1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO CO (US) | 2000-05-10 | — | — | EP | disclosed |
| CN-1052234-C | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2000-05-10 | — | — | CN | disclosed |
| CN-1176642-A | Fungicide for preventing and treating take-all disease of plant | MONSANTO CO (US) | 1998-03-18 | — | — | CN | disclosed |
| EP-0797578-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018631-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1996-06-20 | — | — | WO | disclosed |
| US-5486621-A | 4,5-DOMETHYL-N-2-PROPENYL-2-(TRIMETHYLSILYL)-3-THIOPHENE CARBOXAMIDE | MONSANTO COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042411-A1 | Condensed thiophene compounds and pharmaceutical use thereof | ACIN1, ACHE, TPMT | POLB 1763/4885RECQL 1637/4885GPR35 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.