Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430320 | 0.76 | BACE1 (0.33) | ALDH1A1HPGDBACE1LMNAGAA | |
| SCHEMBL28813678 | 0.76 | ALDH1A1 (0.32) | ALDH1A1BACE1LMNANPY5R | |
| SCHEMBL29842303 | 0.75 | BACE1 (0.37) | ALDH1A1HPGDBACE1KDM4EMAPT | |
| SCHEMBL6002638 | 0.73 | LMNA (0.32) | LMNANPY5R | |
| SCHEMBL9013702 | 0.68 | LMNA (0.38) | ALDH1A1BACE1LMNAGAAPAX8 | |
| SCHEMBL2595557 | 0.67 | LMNA (0.41) | ALDH1A1BACE1LMNAGAAPAX8 | |
| Hydrochloric Acid SCHEMBL2461990 | 0.66 | ALDH1A1 (0.37) | ALDH1A1BACE1LMNAGAAPAX8 | |
| SCHEMBL16919350 | 0.65 | ALDH1A1 (0.33) | ALDH1A1BACE1LMNAGAAPAX8 | |
| SCHEMBL5276695 | 0.63 | ALDH1A1 (0.38) | ALDH1A1BACE1LMNAGAAPAX8 | |
| SCHEMBL11787137 | 0.60 | MMP2 (0.48) | ALDH1A1LMNAGAAPAX8MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907268-B | Method for synthesizing 2H-imidazole compound from aryl methyl ketone compound and ammonium acetate | 湖南第一师范学院 | 2023-11-17 | — | — | CN | disclosed |
| CN-114907268-A | Method for synthesizing 2H-imidazole compound from aryl methyl ketone compound and ammonium acetate | 湖南第一师范学院 | 2022-08-16 | — | — | CN | disclosed |