Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21690043 | 1.00 | L3MBTL1 (0.39) | L3MBTL1CYP1A2OPRK1GAALMNA | |
| SCHEMBL24846026 | 0.88 | L3MBTL1 (0.38) | L3MBTL1OPRK1GAALMNAMAPT | |
| SCHEMBL21643315 | 0.88 | L3MBTL1 (0.38) | L3MBTL1OPRK1GAALMNAMAPT | |
| SCHEMBL21643439 | 0.87 | OPRK1 (0.40) | L3MBTL1OPRK1 | |
| SCHEMBL499202 | 0.87 | OPRK1 (0.40) | L3MBTL1OPRK1 | |
| SCHEMBL21643235 | 0.87 | LMNA (0.50) | L3MBTL1CYP1A2LMNA | |
| SCHEMBL29731103 | 0.87 | KMT2A (0.41) | L3MBTL1OPRK1GAALMNAMAPT | |
| SCHEMBL21643232 | 0.87 | LMNA (0.50) | L3MBTL1CYP1A2LMNA | |
| SCHEMBL21690106 | 0.87 | KMT2A (0.41) | L3MBTL1OPRK1GAALMNAMAPT | |
| SCHEMBL28812499 | 0.87 | KMT2A (0.41) | L3MBTL1OPRK1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746103-A | Rapafucin derivative compounds and methods of use thereof | 约翰霍普金斯大学 | 2022-07-12 | — | — | CN | disclosed |