Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424728 | 0.69 | TSHR (0.73) | TSHRLMNATYRKIF11RAB9A | |
| SCHEMBL12024951 | 0.64 | KCNH2 (0.44) | TSHRLMNATYRKIF11RAB9A | |
| SCHEMBL15370170 | 0.64 | KIF11 (0.42) | TSHRLMNATYRKIF11RAB9A | |
| SCHEMBL2680996 | 0.64 | TSHR (0.39) | TSHRLMNATYRKIF11RAB9A | |
| SCHEMBL20959828 | 0.64 | TSHR (0.39) | TSHRLMNATYRKIF11RAB9A | |
| SCHEMBL24199119 | 0.64 | TSHR (0.44) | TSHRLMNATYRKIF11RAB9A | |
| SCHEMBL33319 | 0.63 | RAB9A (0.73) | TSHRLMNATYRKIF11RAB9A | |
| SCHEMBL18253208 | 0.62 | MAPT (0.51) | TSHRLMNATYRALDH1A1MAPT | |
| SCHEMBL18884520 | 0.62 | TSHR (0.42) | TSHRLMNATYRRAB9ANPC1 | |
| SCHEMBL22629732 | 0.62 | TSHR (0.42) | TSHRLMNATYRKIF11RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907268-B | Method for synthesizing 2H-imidazole compound from aryl methyl ketone compound and ammonium acetate | 湖南第一师范学院 | 2023-11-17 | — | — | CN | disclosed |
| CN-114907268-A | Method for synthesizing 2H-imidazole compound from aryl methyl ketone compound and ammonium acetate | 湖南第一师范学院 | 2022-08-16 | — | — | CN | disclosed |