Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29222876 | 0.84 | SMN1; SMN2 (0.46) | L3MBTL1MAPTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL29222882 | 0.83 | KMT2A (0.48) | MAPTKDM4ESMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL10696390 | 0.83 | HSD17B10 (0.41) | CYP2D6KDM4ETSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL21612891 | 0.82 | GAA (0.47) | L3MBTL1POLBMAPTKDM4ETSHR | |
| SCHEMBL8392193 | 0.82 | L3MBTL1 (0.40) | L3MBTL1POLBCYP2D6MAPTKDM4E | |
| SCHEMBL21050059 | 0.81 | FAAH (0.43) | POLBKDM4ETSHRTP53 | |
| SCHEMBL27341313 | 0.81 | LMNA (0.44) | L3MBTL1POLBCYP2D6KDM4ETSHR | |
| SCHEMBL16879859 | 0.79 | MMP2 (0.43) | POLBELANEMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18259718 | 0.77 | L3MBTL1 (0.51) | L3MBTL1POLBELANECYP2D6MAPT | |
| SCHEMBL10695503 | 0.77 | CYP19A1 (0.41) | CYP2D6KDM4ETSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102413694-B | Imidazole derivatives useful as modulators and imaging agents for FAAH | MERCK SHARP & DOHME | 2014-12-10 | — | — | CN | disclosed |