Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879544 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNARAB9ACPB1HTT | |
| SCHEMBL2881334 | 0.86 | CPB1 (0.42) | SMN1; SMN2LMNAKMT2ACPB1HTT | |
| SCHEMBL2879462 | 0.84 | CYP3A4 (0.52) | LMNACPB1CYP3A4 | |
| SCHEMBL3811557 | 0.82 | CPB1 (0.49) | SMN1; SMN2LMNAKMT2ACPB1HTT | |
| SCHEMBL2878325 | 0.80 | HTT (0.36) | LMNAKMT2ACPB1HTTCYP3A4 | |
| SCHEMBL3807275 | 0.79 | CPB1 (0.40) | SMN1; SMN2LMNARAB9AKMT2ACPB1 | |
| SCHEMBL3812146 | 0.79 | KDM4E (0.41) | RAB9AKMT2AHTTGAAKDM4E | |
| SCHEMBL3807405 | 0.79 | CPB1 (0.43) | SMN1; SMN2KMT2ACPB1HTTCYP3A4 | |
| SCHEMBL3811469 | 0.79 | CPB1 (0.43) | KMT2ACPB1HTTKDM4EATM | |
| SCHEMBL3811147 | 0.78 | CPB1 (0.47) | SMN1; SMN2LMNAKMT2ACPB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |