Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881334 | 0.90 | CPB1 (0.42) | CYP3A4MAPTLMNASLC2A1TP53 | |
| SCHEMBL2881551 | 0.88 | CYP3A4 (0.53) | CYP3A4MAPTLMNASLC2A1TP53 | |
| SCHEMBL3811557 | 0.87 | CPB1 (0.49) | CYP3A4LMNAPOLBCPB1 | |
| SCHEMBL2881336 | 0.84 | SMN1; SMN2 (0.40) | CYP3A4LMNACPB1 | |
| SCHEMBL3811147 | 0.83 | CPB1 (0.47) | CYP3A4MAPTLMNASLC2A1CPB1 | |
| SCHEMBL3815088 | 0.82 | CPB1 (0.43) | CYP3A4MAPTTP53CPB1 | |
| SCHEMBL3811131 | 0.82 | NR1H4 (0.49) | CYP3A4MAPTCPB1 | |
| SCHEMBL3811469 | 0.81 | CPB1 (0.43) | CPB1 | |
| SCHEMBL3807405 | 0.81 | CPB1 (0.43) | CYP3A4CPB1 | |
| SCHEMBL3807293 | 0.79 | KDM4E (0.45) | MAPTLMNACPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |