Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 7/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.46 |
| ▸ | WDR5 | P61964 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27981584 | 0.89 | WDR5 (0.55) | AKR1C3AKR1C4AKR1C2HDAC1AKR1C1 | |
| SCHEMBL1495662 | 0.88 | AKR1C3 (0.55) | AKR1C3AKR1C4AKR1C2HDAC1AKR1C1 | |
| SCHEMBL27981587 | 0.85 | AKR1C3 (0.48) | AKR1C3AKR1C4AKR1C2HDAC1AKR1C1 | |
| SCHEMBL2173876 | 0.84 | P2RX3 (0.50) | AKR1C3AKR1C4AKR1C2HDAC1AKR1C1 | |
| SCHEMBL1495539 | 0.84 | AKR1C3 (0.54) | AKR1C3AKR1C4AKR1C2HDAC1AKR1C1 | |
| SCHEMBL7946501 | 0.83 | HDAC1 (0.53) | AKR1C3AKR1C4AKR1C2HDAC1AKR1C1 | |
| SCHEMBL2383698 | 0.83 | AKR1C3 (0.53) | AKR1C3AKR1C4AKR1C2HDAC1AKR1C1 | |
| SCHEMBL27982185 | 0.82 | P2RX3 (0.47) | P2RX3P2RX2 | |
| SCHEMBL2170971 | 0.81 | P2RX3 (0.67) | AKR1C3AKR1C4AKR1C2HDAC1AKR1C1 | |
| SCHEMBL27981927 | 0.80 | ROCK2 (0.40) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104058999-A | Amide Compounds, Compositions And Uses Thereof | RENOVIS INC | 2014-09-24 | — | — | CN | disclosed |
| CN-104016907-A | Amide compounds, compositions and uses thereof | RENOVIS INC | 2014-09-03 | — | — | CN | disclosed |