Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850416 | 0.76 | HSP90AA1 (0.43) | KDM4EGLA | |
| SCHEMBL27985753 | 0.75 | DHFR (0.33) | KDM4EGLA | |
| Hydrochloric Acid SCHEMBL1367779 | 0.75 | HSP90AA1 (0.41) | KDM4EGLA | |
| SCHEMBL27985752 | 0.73 | ADORA2A (0.44) | KDM4EGLA | |
| SCHEMBL27985443 | 0.72 | KDM4E (0.46) | KDM4ECYP2A6 | |
| SCHEMBL27831916 | 0.72 | PIM1 (0.36) | KDM4EGLA | |
| SCHEMBL28791336 | 0.71 | ADORA2A (0.48) | CYP2A6 | |
| SCHEMBL27985373 | 0.71 | DHFR (0.37) | KDM4EGLAPPARA | |
| SCHEMBL28814482 | 0.70 | ADORA2A (0.47) | KDM4ECYP2A6GLA | |
| SCHEMBL27985802 | 0.70 | PIK3CD (0.35) | KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307869-B | Aminopyrazine derivative and medicine | NIPPON SHINYAKU CO.,LTD. (JP) | 2014-10-22 | — | — | CN | claimed |
| CN-102307869-B | Aminopyrazine derivative and medicine | NIPPON SHINYAKU CO.,LTD. (JP) | 2014-10-22 | — | — | CN | disclosed |