Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 known ✓ | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 known ✓ | P41145 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170617 | 0.88 | OPRM1 (0.38) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL4662387 | 0.85 | OPRM1 (0.37) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL31711370 | 0.85 | OPRM1 (0.37) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1234433 | 0.85 | OPRM1 (0.40) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| Hydroxyamine SCHEMBL27747249 | 0.83 | OPRM1 (0.36) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL20835283 | 0.83 | OPRM1 (0.36) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL28911116 | 0.83 | ALDH1A1 (0.37) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL147493 | 0.83 | TSHR (0.37) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL28754587 | 0.82 | KMT2A (0.34) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| Phosphoric Acid SCHEMBL28205260 | 0.82 | TDP1 (0.37) | OPRM1OPRD1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104302753-A | Compositions comprising lipase and methods of use thereof | NOVOZYMES AS | 2015-01-21 | — | — | CN | disclosed |