Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4662387

C=CCN(CCO)CCO.N

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.37
OPRD1 P41143 4/20 0.37
OPRK1 P41145 4/20 0.37
TSHR P16473 1/20 0.35
KDM4E B2RXH2 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 2/20 0.30
ALOX15 P16050 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170617 0.97 OPRM1 (0.38) OPRM1OPRD1OPRK1TSHRKDM4E
SCHEMBL31711370 0.94 OPRM1 (0.37) OPRM1OPRD1OPRK1TSHRKDM4E
Hydrochloric Acid SCHEMBL1234433 0.94 OPRM1 (0.40) OPRM1OPRD1OPRK1TSHRKDM4E
Hydroxyamine SCHEMBL27747249 0.92 OPRM1 (0.36) OPRM1OPRD1OPRK1TSHRKDM4E
SCHEMBL20835283 0.92 OPRM1 (0.36) OPRM1OPRD1OPRK1TSHRKDM4E
SCHEMBL147493 0.92 TSHR (0.37) OPRM1OPRD1OPRK1TSHRKDM4E
Hydrochloric Acid SCHEMBL7722967 0.89 OPRK1 (0.36) OPRM1OPRD1OPRK1TSHRKDM4E
Trolamine SCHEMBL9856574 0.89 TSHR (0.35) OPRM1OPRD1OPRK1TSHRKDM4E
Bromide SCHEMBL11042426 0.89 KDM4E (0.35) OPRM1OPRD1OPRK1TSHRKDM4E
SCHEMBL3809578 0.87 OPRM1 (0.34) OPRM1OPRD1OPRK1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017099956-A1 FUNCTIONAL FLUID COMPOSITIONS CONTAINING EROSION INHIBITORS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-06-15 WO disclosed
US-20170158981-A1 FUNCTIONAL FLUID COMPOSITIONS CONTAINING EROSION INHIBITORS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-06-08 US disclosed
EP-1920033-A2 AVIATION PHOSPHATE ESTER FUNCTIONAL FLUIDS WITH ENHANCED ACID SCAVENGING PROPERTIES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-05-14 EP disclosed
WO-2007011783-A2 AVIATION PHOSPHATE ESTER FUNCTIONAL FLUIDS WITH ENHANCED ACID SCAVENGING PROPERTIES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-01-25 WO disclosed
US-20070021311-A1 Aviation phosphate ester functional fluids with enhanced acid scavenging properties EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-01-25 US disclosed
US-6703355-B2 FIRE RESISTANT PHOSPHATE ESTERS BASE STOCK, A VISCOSITY INDEX IMPROVER, AN ANTICORROSION AGENT, AND ACID SCAVENGER; AIRCRAFT USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2004-03-09 US disclosed
US-20040026566-A1 Method for lubricating high pressure hydraulic system using phosphate ester hydraulic fluid ANTIKA SHLOMO (US) 2004-02-12 US disclosed
US-20030060377-A1 Fire resistant phosphate esters base stock, a viscosity index improver, an anticorrosion agent, and acid scavenger; aircraft use EXXONMOBIL RESEARCH & ENGINEERING CO. 2003-03-27 US disclosed
WO-2002012777-A2 METHOD FOR LUBRICATING HIGH PRESSURE HYDRAULIC SYSTEM USING PHOSPHATE ESTER HYDRAULIC FLUID EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2002-02-14 WO disclosed