Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27996561 | 0.98 | IDO1 (0.48) | SIGMAR1L3MBTL1TDP1IDO1MEN1 | |
| SCHEMBL1720772 | 0.92 | IDO1 (0.55) | SIGMAR1L3MBTL1IDO1MEN1KMT2A | |
| SCHEMBL450596 | 0.84 | CA1 (0.44) | SIGMAR1TDP1IDO1MEN1KMT2A | |
| SCHEMBL97332 | 0.81 | SIGMAR1 (0.52) | SIGMAR1IDO1 | |
| SCHEMBL96962 | 0.81 | SIGMAR1 (0.52) | SIGMAR1IDO1 | |
| SCHEMBL2517 | 0.78 | SIGMAR1 (0.48) | SIGMAR1IDO1MAOA | |
| SCHEMBL7590883 | 0.78 | IDO1 (0.48) | SIGMAR1L3MBTL1TDP1IDO1MAOA | |
| SCHEMBL8499231 | 0.78 | L3MBTL1 (0.57) | SIGMAR1L3MBTL1TDP1IDO1MAOA | |
| SCHEMBL8498124 | 0.78 | L3MBTL1 (0.57) | SIGMAR1L3MBTL1TDP1IDO1MAOA | |
| SCHEMBL8499737 | 0.78 | L3MBTL1 (0.57) | SIGMAR1L3MBTL1TDP1IDO1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104302644-A | Thiazolecarboxamide derivatives and methods of use thereof | NIHON NOHYAKU CO LTD | 2015-01-21 | — | — | CN | disclosed |