Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96962 | 1.00 | SIGMAR1 (0.52) | SIGMAR1MAPTRXFP1IDO1FFAR1 | |
| SCHEMBL2517 | 0.98 | SIGMAR1 (0.48) | SIGMAR1MAPTRXFP1IDO1FFAR1 | |
| SCHEMBL5547690 | 0.95 | TDP1 (0.49) | SIGMAR1MAPTRXFP1IDO1FFAR1 | |
| SCHEMBL2961385 | 0.95 | TDP1 (0.49) | SIGMAR1MAPTRXFP1IDO1FFAR1 | |
| SCHEMBL96791 | 0.95 | TDP1 (0.49) | SIGMAR1MAPTRXFP1IDO1FFAR1 | |
| SCHEMBL5546766 | 0.95 | TDP1 (0.49) | SIGMAR1MAPTRXFP1IDO1FFAR1 | |
| SCHEMBL5537354 | 0.95 | TDP1 (0.49) | SIGMAR1MAPTRXFP1IDO1FFAR1 | |
| SCHEMBL5544777 | 0.95 | TDP1 (0.49) | SIGMAR1MAPTRXFP1IDO1FFAR1 | |
| SCHEMBL5545719 | 0.95 | TDP1 (0.49) | SIGMAR1MAPTRXFP1IDO1FFAR1 | |
| SCHEMBL5543105 | 0.95 | TDP1 (0.49) | SIGMAR1MAPTRXFP1IDO1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7750185-B2 | Photoactive materials | ROLIC AG (CH) | 2010-07-06 | — | — | US | claimed |
| US-20050288480-A1 | Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked | ROLIC AG (CH) | 2005-12-29 | — | — | US | claimed |
| EP-1525182-A1 | PHOTOACTIVE MATERIALS | Rolic AG (CH) | 2005-04-27 | — | — | EP | claimed |
| WO-2004013086-A1 | PHOTOACTIVE MATERIALS | ROLIC AG (CH) | 2004-02-12 | — | — | WO | claimed |
| EP-1386910-A1 | Photoactive materials | Rolic AG (CH) | 2004-02-04 | — | — | EP | claimed |
| WO-2024075815-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | 国立大学法人大阪大学 | 2024-04-11 | — | — | WO | disclosed |
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| EP-3022199-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2016-05-25 | — | — | EP | disclosed |
| EP-1525182-B1 | PHOTOACTIVE MATERIALS | ROLIC AG (CH) | 2016-04-06 | — | — | EP | disclosed |
| US-4950662-A | ANTIBIOTIC | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4898859-A | 2-Oxa-isocephem compounds and compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| US-4859759-A | Siloxane containing benzotriazolyl/tetraalkylpiperidyl substituent | KIMBERLY-CLARK CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |
| EP-0287951-A2 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |
| EP-0282895-A2 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | SIGMAR1 4091/4885MAPT 2196/4885RXFP1 2555/4885 |
| US-20050288480-A1 | Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked | C9, F12, DAO | SIGMAR1 3813/4885MAPT 318/4885RXFP1 2236/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | SIGMAR1 4091/4885MAPT 2196/4885RXFP1 2555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.