SCHEMBL28816355

SCHEMBL28816355

CS(=O)(=O)c1ccccc1NC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.53
CNR2 P34972 1/20 0.47
CA1 P00915 9/20 0.45
CA2 P00918 9/20 0.45
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
PABPC1 P11940 1/20 0.43
EIF4H Q15056 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
ADRA1A P35348 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HTR6 P50406 1/20 0.42
POLB P06746 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7108586 0.86 NPC1 (0.53) BCAT2CNR2CA1CA2CA12
SCHEMBL2575446 0.85 CA1 (0.49) BCAT2CNR2CA1CA2CA12
SCHEMBL1644002 0.85 ALDH1A1 (0.55) BCAT2CA1CA2CA9ALDH1A1
SCHEMBL30752023 0.85 CA1 (0.49) BCAT2CNR2CA1CA2CA12
SCHEMBL4748579 0.81 CA1 (0.45) CA1CA2CA12CA9ALDH1A1
SCHEMBL3831588 0.80 ADRA2A (0.44) CA1CA2CA12CA9NPC1
SCHEMBL10991718 0.79 HTR6 (0.62) CA1CA2CA12CA9NPC1
SCHEMBL27698527 0.79 CA1 (0.51) BCAT2CA1CA2ADRA1AALDH1A1
SCHEMBL5483549 0.78 L3MBTL1 (0.50) BCAT2CNR2CA1CA2ADRA1A
SCHEMBL10727900 0.78 HTR6 (0.56) CA2CA12CA9NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102015651-B Compounds and compositions as TLR activity modulators IRM LLC 2014-12-31 CN disclosed