Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 6/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835434 | 1.00 | KYNU (0.44) | KYNUCTSLCTSKCTSSCTSB | |
| SCHEMBL28816503 | 0.92 | CTSK (0.42) | KYNUCTSLCTSKCTSSCTSB | |
| SCHEMBL27998434 | 0.89 | BCHE (0.44) | KYNUCTSLCTSKCTSSCTSB | |
| SCHEMBL478953 | 0.86 | KYNU (0.44) | KYNUCTSLCTSKCTSSSYK | |
| SCHEMBL478951 | 0.86 | KYNU (0.44) | KYNUCTSLCTSKCTSSSYK | |
| SCHEMBL3410144 | 0.81 | KYNU (0.50) | KYNUCTSLCTSKCTSSCTSB | |
| SCHEMBL478461 | 0.80 | ACKR3 (0.46) | CTSLCTSKCTSSCTSBBCHE | |
| SCHEMBL478463 | 0.80 | ACKR3 (0.46) | CTSLCTSKCTSSCTSBBCHE | |
| Tert-Butyl Formate SCHEMBL27835436 | 0.78 | KYNU (0.43) | KYNUCTSLCTSKCTSSCTSB | |
| SCHEMBL478742 | 0.78 | YAP1 (0.45) | CTSLBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026996-B | Pyridazine derivatives as factor XIA inhibitors | BRISTOL MYERS SQUIBB CO | 2015-01-07 | — | — | CN | disclosed |