Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049253 | 0.86 | LMNA (0.47) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28086157 | 0.86 | LMNA (0.51) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27999947 | 0.84 | GAA (0.53) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL28314858 | 0.84 | LMNA (0.54) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27995211 | 0.83 | ATM (0.41) | MEN1KMT2AOPRM1CYP2D6 | |
| SCHEMBL27996405 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2A | |
| SCHEMBL27968133 | 0.82 | ATM (0.38) | MEN1KMT2AOPRD1CYP2D6 | |
| SCHEMBL28299375 | 0.81 | KCNA3 (0.43) | OPRD1OPRM1CYP1A2CYP2D6 | |
| SCHEMBL28049321 | 0.79 | ALDH1A1 (0.40) | MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28026010 | 0.79 | ALDH1A1 (0.38) | CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923114-A | Pyrazolopyridine derivatives as HPK1 modulators and their use for the treatment of cancer | 因赛特公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-104011045-B | Dihydrobenzoxazine and dihydropyridinooxazine derivatives | 诺华股份有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-102918042-B | 8-methyl-1-phenyl-imidazo [1,5-a ] pyrazine compounds | MERCK SHARP & DOHME B.V. (NL) | 2016-03-09 | — | — | CN | disclosed |
| CN-104981457-A | Heterocyclic compound | TAKEDA PHARMACEUTICAL | 2015-10-14 | — | — | CN | disclosed |
| CN-104662015-A | Complement pathway modulators and uses thereof | NOVARTIS AG | 2015-05-27 | — | — | CN | disclosed |
| CN-104603146-A | Cyclic peptides and use as medicines | NOVARTIS AG | 2015-05-06 | — | — | CN | disclosed |
| CN-104379576-A | Substituted pyrrolidines as factor XIA inhibitors for the treatment of thromboembolic disorders | ONO PHARMACEUTICAL CO | 2015-02-25 | — | — | CN | disclosed |