Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562917 | 0.87 | KDM4E (0.53) | AURKATPX2FFAR4DDR1NOTUM | |
| SCHEMBL28000100 | 0.85 | ALDH1A1 (0.44) | MAPK1FFAR4DDR1 | |
| SCHEMBL16527926 | 0.85 | LMNA (0.48) | DDR1 | |
| SCHEMBL2565319 | 0.84 | KMO (0.56) | AURKATPX2FFAR4DDR1 | |
| SCHEMBL9104053 | 0.81 | KCNA5 (0.62) | KCNA5MAPK1RORCFFAR4 | |
| SCHEMBL27999922 | 0.81 | NOTUM (0.61) | ENPP2KCNA5MAPK1FFAR4NOTUM | |
| SCHEMBL27999970 | 0.78 | MGLL (0.53) | DDR1MGLL | |
| SCHEMBL5238137 | 0.78 | KCNA5 (0.58) | KCNA5AURKATPX2MAPK1RORC | |
| SCHEMBL475754 | 0.75 | AURKA (0.56) | AURKATPX2 | |
| SCHEMBL31550001 | 0.75 | AURKA (0.56) | AURKATPX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379560-A | Benzamide derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |