Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 6/20 | 0.38 |
| ▸ | JAK1 | P23458 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL28000605 | 0.98 | MEN1 (0.40) | MEN1KMT2AABCB11ADORA3AR | |
| SCHEMBL4168246 | 0.96 | MEN1 (0.43) | MEN1KMT2AABCB11ADORA3AR | |
| SCHEMBL4173780 | 0.94 | MEN1 (0.42) | MEN1KMT2AABCB11ADORA3AR | |
| SCHEMBL5706202 | 0.94 | MEN1 (0.42) | MEN1KMT2AABCB11ADORA3AR | |
| SCHEMBL3717754 | 0.86 | CYP2A6 (0.36) | MEN1KMT2ASLC6A4HTTHRH3 | |
| SCHEMBL4485887 | 0.86 | HRH4 (0.44) | MEN1KMT2AJAK3JAK1JAK2 | |
| SCHEMBL6608762 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AJAK3JAK1JAK2 | |
| Methylamine SCHEMBL28000435 | 0.81 | KDM4E (0.47) | MEN1KMT2AJAK3JAK1JAK2 | |
| SCHEMBL7793337 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AJAK3JAK1JAK2 | |
| SCHEMBL25353462 | 0.78 | KDM1A (0.38) | MEN1KMT2AKCNH2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104356002-A | Preparation process of impurities contained in expectorant drug bromhexine hydrochloride | UNIV HEBEI MEDICAL | 2015-02-18 | — | — | CN | claimed |
| CN-104356002-A | Preparation process of impurities contained in expectorant drug bromhexine hydrochloride | UNIV HEBEI MEDICAL | 2015-02-18 | — | — | CN | disclosed |