Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 5/20 | 0.36 |
| ▸ | JAK1 | P23458 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706202 | 1.00 | MEN1 (0.42) | MEN1KMT2ATRPV1HRH4HRH3 | |
| SCHEMBL4168246 | 0.98 | MEN1 (0.43) | MEN1KMT2ATRPV1HRH4HRH3 | |
| Methylamine SCHEMBL28816853 | 0.94 | MEN1 (0.41) | MEN1KMT2ATRPV1HRH4HRH3 | |
| Methylamine SCHEMBL28000605 | 0.93 | MEN1 (0.40) | MEN1KMT2ATRPV1HRH4HRH3 | |
| SCHEMBL3717754 | 0.88 | CYP2A6 (0.36) | MEN1KMT2AHRH3SLC6A4HTT | |
| SCHEMBL4485887 | 0.88 | HRH4 (0.44) | MEN1KMT2ATRPV1HRH4HRH3 | |
| SCHEMBL7793337 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2ATRPV1HRH4HRH3 | |
| SCHEMBL25353462 | 0.79 | KDM1A (0.38) | MEN1KMT2AKCNH2LMNAHTT | |
| SCHEMBL26011715 | 0.79 | NMT1 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15013072 | 0.78 | TRPA1 (0.49) | TRPV1HRH4HRH3KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111781-A1 | Use of Cymipristone Type Compounds in Aids Treatment | SHANGHAI THREE-ALLIANCE BIOTECHNOLOGIES CO., LTD. (CN) | 2009-04-30 | — | — | US | disclosed |
| EP-1911450-A1 | USE OF CYMIPRISTONES FOR TREATING AIDS | Shanghai Three-alliance Biotechnologies Co., Ltd. (CN) | 2008-04-16 | — | — | EP | disclosed |
| CN-1899289-A | Use of symipristone compound for treating AIDS | SANHE BIOLOG TECHNOLOGY CO LTD (CN) | 2007-01-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111781-A1 | Use of Cymipristone Type Compounds in Aids Treatment | NR3C1, NR3C2, NR5A1 | MEN1 3687/4885KMT2A 1179/4885TRPV1 1724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.