Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.39 |
| ▸ | LPL | P06858 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28817245 | 0.95 | F11 (0.42) | F11CA1CA2CA9F2 | |
| SCHEMBL16050222 | 0.88 | LIPG (0.40) | F11CA1CA2CA9F2 | |
| SCHEMBL19951603 | 0.82 | HSD11B1 (0.36) | F11CA1CA2CA9F2 | |
| SCHEMBL6059 | 0.78 | GAA (0.49) | F11CA1CA2CA9F2 | |
| SCHEMBL14710585 | 0.77 | DGAT1 (0.41) | F11CA1CA2CA9F2 | |
| SCHEMBL12327234 | 0.77 | LIPG (0.47) | F11CA1CA2CA9F2 | |
| SCHEMBL28490255 | 0.77 | CA1 (0.44) | F11CA1CA2CA9F2 | |
| SCHEMBL5336869 | 0.76 | F11 (0.56) | F11CA1CA2CA9F2 | |
| SCHEMBL3680238 | 0.76 | F11 (0.48) | F11CA1CA2CA9F2 | |
| SCHEMBL14790219 | 0.75 | LIPG (0.53) | F11CA1CA2CA9LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341774-B | Substituted quinolinone inhibitors | 首药控股(北京)股份有限公司 | 2022-07-19 | — | — | CN | disclosed |