Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15774912 | 0.82 | F11 (0.48) | DGAT1F11F2PRSS1PRSS2 | |
| SCHEMBL23305795 | 0.79 | F11 (0.48) | DGAT1F11F2PRSS1PRSS2 | |
| SCHEMBL15774694 | 0.78 | F11 (0.52) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5336869 | 0.77 | F11 (0.56) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL15774945 | 0.76 | LPL (0.49) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL15775042 | 0.76 | LPL (0.49) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2282563 | 0.76 | F11 (0.37) | DGAT1F11F2PRSS1PRSS2 | |
| SCHEMBL16112518 | 0.75 | LIPG (0.56) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4482694 | 0.75 | LPL (0.54) | F11CA1CA2CA9P4HB | |
| SCHEMBL10458 | 0.74 | DGAT1 (0.53) | DGAT1F11F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341774-B | Substituted quinolinone inhibitors | 首药控股(北京)股份有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-107573295-B | Molecules and intermediates having pesticidal utility, compositions and methods relating thereto | 美国陶氏益农公司 | 2020-12-15 | — | — | CN | disclosed |