SCHEMBL28817550

SCHEMBL28817550

C#Cc1ccccc1CC#N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
FFAR1 O14842 4/20 0.42
FFAR4 Q5NUL3 2/20 0.42
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP1B1 Q16678 1/20 0.40
TSPO P30536 1/20 0.38
DRD3 P35462 1/20 0.38
CSNK2A1 P68400 1/20 0.33
CYP19A1 P11511 1/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HTT P42858 1/20 0.32
TSHR P16473 1/20 0.32
GRIA1 P42261 1/20 0.32
CACNG8 Q8WXS5 1/20 0.32
ATP4A P20648 1/20 0.32
ATP4B P51164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820195 0.82 ALDH1A1 (0.47) ALDH1A1HPGDFFAR1FFAR4CYP1A1
SCHEMBL30409781 0.82 ALDH1A1 (0.47) ALDH1A1HPGDFFAR1FFAR4CYP1A1
SCHEMBL29809738 0.78 ALDH1A1 (0.56) ALDH1A1HPGDFFAR1FFAR4CYP1A1
SCHEMBL1945874 0.78 ALDH1A1 (0.56) ALDH1A1HPGDFFAR1FFAR4CYP1A1
SCHEMBL9862093 0.77 HSPA5 (0.40) CYP1A1CYP1A2CYP1B1
SCHEMBL4170188 0.75 TRPA1 (0.36) ALDH1A1CYP1A1CYP1A2CYP1B1TSHR
SCHEMBL29074205 0.74 FFAR1 (0.64) ALDH1A1HPGDFFAR1FFAR4CYP1A2
SCHEMBL28463170 0.74 ALDH1A1 (0.46) ALDH1A1HPGDFFAR1FFAR4TSPO
SCHEMBL1020369 0.73 IDO1 (0.50) ALDH1A1HPGDCYP1A2TSHRGRIA1
SCHEMBL149728 0.73 APOBEC3G (0.43) ALDH1A1HPGDFFAR1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114910541-B Electrochemical sensor and preparation method and application thereof 华南理工大学 2023-06-20 CN disclosed
CN-114910541-A Electrochemical sensor and preparation method and application thereof 华南理工大学 2022-08-16 CN disclosed