SCHEMBL9862093

SCHEMBL9862093

C#Cc1ccccc1Cc1ccccc1C#C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.40
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP1B1 Q16678 1/20 0.36
PYCR1 P32322 2/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
PNMT P11086 1/20 0.32
IDO1 P14902 1/20 0.32
TAAR1 Q96RJ0 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2870972 0.86 CALM1 (0.46)
SCHEMBL4170188 0.82 TRPA1 (0.36) CYP1A1CYP1A2CYP1B1PYCR1PNMT
SCHEMBL26987968 0.81 PYCR1 (0.39) PYCR1TAAR1
SCHEMBL7061714 0.80 ALDH1A1 (0.38) CYP1A1CYP1A2CYP1B1PYCR1PNMT
SCHEMBL149728 0.80 APOBEC3G (0.43) HSPA5CYP1A1CYP1A2CYP1B1PYCR1
SCHEMBL4953056 0.80 GABRA1 (0.46) PYCR1GABRA1GABRB2
SCHEMBL1253891 0.80 CYP1A1 (0.33) CYP1A1CYP1A2CYP1B1PYCR1GABRA1
SCHEMBL6679575 0.80 IDO1 (0.50) CYP1A1CYP1A2CYP1B1PYCR1PNMT
SCHEMBL20838091 0.80 CYP1A1 (0.33) CYP1A1CYP1A2CYP1B1PYCR1PNMT
SCHEMBL3973809 0.80 PNMT (0.50) CYP1A1CYP1A2CYP1B1PYCR1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991009066-A1 HIGH CARBON RESINS AND FOAMS HYPERION CATALYSIS INTERNATIONAL, INC. (US) 1991-06-27 WO disclosed