SCHEMBL28817754

SCHEMBL28817754

C=Cc1c(-c2ccccc2)ccc2cc3ccccc3cc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.40
KMT2A Q03164 6/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 3/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 1/20 0.40
MPI P34949 1/20 0.40
PTGS2 P35354 1/20 0.37
HIF1A Q16665 1/20 0.36
CYP1B1 Q16678 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
RAB9A P51151 2/20 0.34
MAPK1 P28482 2/20 0.34
MITF O75030 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8168394 0.86 GABRA1 (0.35) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL2354609 0.84 ALDH1A1 (0.41) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL423136 0.81 ESR1 (0.35) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL5947026 0.80 ESR1 (0.39) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL5548833 0.78 THRB (0.41) MEN1KMT2AHSD17B10
SCHEMBL28448580 0.78 KDM4E (0.38) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL29738324 0.78 KDM4E (0.38) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL5551487 0.77 RARB (0.41) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL27898117 0.77 ALDH1A1 (0.43) ALDH1A1HPGDPTGS2HSD17B10ESR2
SCHEMBL5068229 0.77 ALDH1A1 (0.40) MEN1KMT2AALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801319-A AIE-based high tensile SP/H 8 Preparation and application of ETTB double-network reversible color-changing hydrogel 中北大学 2024-04-02 CN disclosed
CN-114656398-A Application of aggregation-induced emission photosensitizer in preparation of iron death inducer 郑州大学 2022-06-24 CN disclosed
CN-104350627-A Material for light-emitting element and light-emiting element TORAY INDUSTRIES 2015-02-11 CN disclosed