Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551487 | 0.99 | RARB (0.41) | THRBRARBHSD11B1BCHECTSV | |
| SCHEMBL6059713 | 0.80 | TLR8 (0.49) | RARBHSD11B1BCHECTSVCTSL | |
| SCHEMBL3731391 | 0.80 | BCHE (0.41) | RARBHSD11B1BCHECTSVCTSL | |
| SCHEMBL28891102 | 0.79 | TLR8 (0.48) | RARBHSD11B1CTSVCTSLGPR3 | |
| SCHEMBL28382831 | 0.79 | TLR8 (0.48) | RARBHSD11B1CTSVCTSLGPR3 | |
| SCHEMBL27730560 | 0.79 | TLR8 (0.48) | RARBHSD11B1CTSVCTSLGPR3 | |
| SCHEMBL28817754 | 0.78 | MEN1 (0.40) | MEN1KMT2AHSD17B10 | |
| SCHEMBL8715524 | 0.78 | TLR8 (0.41) | THRBTHRAMEN1KMT2ATLR8 | |
| SCHEMBL6059211 | 0.77 | HSD11B1 (0.49) | RARBHSD11B1BCHEMEN1KMT2A | |
| SCHEMBL8718986 | 0.77 | THRA (0.43) | THRBTHRAMEN1KMT2ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869720-A2 | ARYL-ETHYLENE SUBSTITUTED AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC SEMICONDUCTORS | E.I.Du pont de nemours and company (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006113205-A2 | ARYL-ETHYLENE SUBSTITUTED AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC SEMICONDUCTORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-10-26 | — | — | WO | disclosed |