Pyridine

Pyridine

SCHEMBL28817862

O=c1cccc2oc3ccccc3nc1-2.c1ccncc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
ALDH1A1 P00352 6/20 0.43
RAB9A P51151 6/20 0.43
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
KDM4E B2RXH2 3/20 0.43
ALPL P05186 1/20 0.43
POLB P06746 1/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
RECQL P46063 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NR1I2 O75469 1/20 0.43
CHRM1 P11229 1/20 0.43
DRD2 P14416 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
CHRM3 P20309 1/20 0.43
MAOA P21397 1/20 0.43
HTR2C P28335 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29631752 0.91 MAPT (0.50) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL306543 0.91 MAPT (0.50) MAPTALDH1A1RAB9AMEN1KMT2A
Hydrochloric Acid SCHEMBL10485854 0.89 MAPT (0.49) MAPTALDH1A1RAB9AMEN1KMT2A
Perchlorate SCHEMBL11026726 0.82 MAPT (0.43) MAPTALDH1A1RAB9AMEN1KMT2A
Nitric Acid SCHEMBL11293599 0.81 MAPT (0.43) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL3666115 0.72 RAB9A (0.46) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL29196821 0.71 ALOX5 (0.45) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL28612367 0.71 APP (0.54) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL3276944 0.70 MEN1 (0.56) MAPTALDH1A1RAB9AMEN1KMT2A
Pyridine SCHEMBL2147801 0.69 ALDH1A1 (0.47) MAPTALDH1A1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773329-B Phenoxazinone pyridinium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2023-04-14 CN claimed
CN-114773329-A Phenoxazinone pyridinium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2022-07-22 CN claimed
CN-114773329-B Phenoxazinone pyridinium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2023-04-14 CN disclosed
CN-114773329-B Phenoxazinone pyridinium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2023-04-14 CN disclosed
CN-114773329-B Phenoxazinone pyridinium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2023-04-14 CN disclosed
CN-114773329-A Phenoxazinone pyridinium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2022-07-22 CN disclosed
CN-114773329-A Phenoxazinone pyridinium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2022-07-22 CN disclosed
CN-114773329-A Phenoxazinone pyridinium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2022-07-22 CN disclosed