Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306543 | 0.77 | MAPT (0.50) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL29631752 | 0.77 | MAPT (0.50) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL2609273 | 0.76 | MEN1 (0.62) | MEN1KMT2AMAPTRAB9APOLB | |
| Hydrochloric Acid SCHEMBL10485854 | 0.76 | MAPT (0.49) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL20362084 | 0.75 | MAPT (0.52) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL31011137 | 0.75 | MAOA (0.68) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL31033251 | 0.75 | RAB9A (0.52) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL16431722 | 0.75 | MAOA (0.68) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL1635786 | 0.73 | MAPT (0.54) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL10941393 | 0.73 | MEN1 (0.51) | MEN1KMT2AMAPTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140080794-A1 | Methods and Compositions for the Treatment of Estrogen-Dependent Hyperproliferative Uterine Disorders | VIVUS INC (US) | 2014-03-20 | — | — | US | disclosed |
| US-20100087402-A1 | Methods and compositions for the treatment of estrogen-dependent hyperproliferative uterine disorders | VIVUS, INC. (US) | 2010-04-08 | — | — | US | disclosed |