Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ATR | Q13535 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.30 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225207 | 0.72 | AGBL2 (0.33) | AGBL2KDM4E | |
| SCHEMBL11167289 | 0.68 | ALDH1A1 (0.39) | AGBL2KDM4EALDH1A1HPGD | |
| SCHEMBL10912828 | 0.68 | SCN4A (0.32) | AGBL2GRM5GPR139 | |
| SCHEMBL13341567 | 0.67 | AGBL2 (0.32) | AGBL2 | |
| SCHEMBL11174630 | 0.65 | — | — | |
| SCHEMBL309283 | 0.61 | KDM4E (0.43) | KDM4EALDH1A1ATR | |
| SCHEMBL15348810 | 0.60 | KDM4E (0.54) | KDM4ENPC1RAB9AGRM5SMN1; SMN2 | |
| SCHEMBL21067103 | 0.60 | AGBL2 (0.40) | AGBL2ALDH1A1NPC1RAB9AP4HTM | |
| SCHEMBL22834990 | 0.60 | ATR (0.41) | ATR | |
| SCHEMBL308924 | 0.60 | KDM4E (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102548979-B | 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives | DOW AGROSCIENCES LLC | 2015-05-13 | — | — | CN | disclosed |