Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | AIP | O00170 | 1/20 | 0.50 |
| ▸ | SGTA | O43765 | 1/20 | 0.50 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.50 |
| ▸ | STIP1 | P31948 | 1/20 | 0.50 |
| ▸ | PPP5C | P53041 | 1/20 | 0.50 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.50 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.50 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.50 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289674 | 0.81 | ALDH1A1 (0.80) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL3914480 | 0.79 | MAPT (1.00) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL681864 | 0.77 | ALDH1A1 (0.80) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL8288649 | 0.77 | KMT2A (0.80) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL8288773 | 0.75 | MAPT (0.61) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL2489815 | 0.72 | POLB (0.62) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL6435364 | 0.71 | KMT2A (0.85) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL18177310 | 0.71 | MAPT (0.61) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL3914440 | 0.70 | MEN1 (1.00) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL6472036 | 0.70 | KMT2A (0.69) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104357545-B | The medicine pocket of a kind of S adenosylmethionine decarboxylase and application thereof | CHINA THREE GORGES UNIVERSITY (CN) | 2016-06-01 | — | — | CN | claimed |
| CN-104357545-B | The medicine pocket of a kind of S adenosylmethionine decarboxylase and application thereof | CHINA THREE GORGES UNIVERSITY (CN) | 2016-06-01 | — | — | CN | disclosed |
| CN-104357545-A | Drug pocket of AdoMetDC (S-adenosylmethionine decarboxylase) and application of drug pocket | UNIV CHINA THREE GORGES CTGU | 2015-02-18 | — | — | CN | disclosed |