Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AIP | O00170 | 1/20 | 0.48 |
| ▸ | SGTA | O43765 | 1/20 | 0.48 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.48 |
| ▸ | STIP1 | P31948 | 1/20 | 0.48 |
| ▸ | PPP5C | P53041 | 1/20 | 0.48 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14586394 | 0.85 | ALDH1A1 (0.48) | MAPTLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL681864 | 0.83 | ALDH1A1 (0.80) | MAPTLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL1520444 | 0.75 | MAPT (0.61) | MAPTLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL2760504 | 0.71 | MAPT (0.60) | MAPTLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL3285724 | 0.71 | ALDH1A1 (0.79) | MAPTLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL18177310 | 0.68 | MAPT (0.61) | MAPTLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL3918756 | 0.67 | ALDH1A1 (0.70) | MAPTLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL3279956 | 0.66 | MAPT (0.61) | MAPTLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL3453384 | 0.65 | LMNA (0.64) | MAPTLMNAPOLBALDH1A1KMT2A | |
| SCHEMBL8288774 | 0.64 | GRM1 (0.66) | MAPTALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |