Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.39 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29871289 | 0.90 | ALDH1A1 (0.46) | P2RX7ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL23648657 | 0.90 | ALDH1A1 (0.46) | P2RX7ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL23648784 | 0.89 | ALDH1A1 (0.45) | P2RX7PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL29870905 | 0.84 | ALDH1A1 (0.45) | P2RX7ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL23648608 | 0.84 | ALDH1A1 (0.45) | P2RX7ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29870825 | 0.84 | HSD17B10 (0.41) | P2RX7ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL23648614 | 0.84 | HSD17B10 (0.41) | P2RX7ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL23648604 | 0.84 | F2 (0.48) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29871276 | 0.84 | F2 (0.48) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL23656497 | 0.83 | P2RX7 (0.48) | P2RX7ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945561-A | Novel pyrazole derivatives | 阿普塔生物治疗公司 | 2022-08-26 | — | — | CN | claimed |
| CN-114945561-A | Novel pyrazole derivatives | 阿普塔生物治疗公司 | 2022-08-26 | — | — | CN | disclosed |