SCHEMBL23648657

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29871289	1.00	ALDH1A1 (0.46)	ALDH1A1MAPK1SLC6A7L3MBTL1GRM5
	SCHEMBL23656497	0.91	P2RX7 (0.48)	ALDH1A1MAPK1SLC6A7L3MBTL1GRM5
	SCHEMBL28818366	0.90	P2RX7 (0.41)	ALDH1A1MAPK1SLC6A7L3MBTL1P2RX7
	SCHEMBL23648784	0.86	ALDH1A1 (0.45)	ALDH1A1F12P2RX7HPGDTSHR
	SCHEMBL23656488	0.84	ALDH1A1 (0.52)	ALDH1A1MAPK1F12P2RX7KDM4E
	SCHEMBL29870825	0.81	HSD17B10 (0.41)	ALDH1A1MAPK1F12P2RX7KDM4E
	SCHEMBL29870905	0.81	ALDH1A1 (0.45)	ALDH1A1MAPK1L3MBTL1GRM5F12
	SCHEMBL23648608	0.81	ALDH1A1 (0.45)	ALDH1A1MAPK1L3MBTL1GRM5F12
	SCHEMBL23648614	0.81	HSD17B10 (0.41)	ALDH1A1MAPK1F12P2RX7KDM4E
	SCHEMBL23648604	0.81	F2 (0.48)	ALDH1A1GRM5F12MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.