Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844133 | 0.85 | C5AR1 (0.46) | P2RX7BRD4CREBBPKDM2BKDM4C | |
| SCHEMBL30045599 | 0.81 | P2RX7 (0.40) | P2RX7BRD4CREBBPKDM2BKDM4C | |
| SCHEMBL28818558 | 0.80 | KCNK3 (0.48) | P2RX7BRD4CREBBPKDM2BKDM4C | |
| SCHEMBL29844044 | 0.79 | HTR2A (0.39) | P2RX7BRD4CREBBPKDM2BKDM4C | |
| SCHEMBL23577483 | 0.78 | P2RX7 (0.40) | P2RX7BRD4CREBBPKDM2BKDM4C | |
| SCHEMBL21819349 | 0.73 | P2RX7 (0.67) | P2RX7BRD4CREBBPDPP4DPP8 | |
| Hydrochloric Acid SCHEMBL29844125 | 0.71 | HTR2C (0.46) | GRM5HTR2AHTR2CHTR2BTDP2 | |
| SCHEMBL28818541 | 0.71 | MAPK1 (0.49) | P2RX7BRD4CREBBP | |
| SCHEMBL31163256 | 0.70 | MAPK1 (0.46) | P2RX7BRD4CREBBPKCNK3DPP4 | |
| SCHEMBL21893715 | 0.70 | P2RX7 (0.50) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | disclosed |