Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844211 | 0.85 | CTSS (0.46) | KCNK3CREBBPBRD4SPTLC1P2RX7 | |
| SCHEMBL28739860 | 0.84 | P2RX7 (0.55) | CREBBPSPTLC1P2RX7 | |
| SCHEMBL30044769 | 0.81 | SPTLC1 (0.49) | KCNK3CREBBPBRD4SPTLC1P2RX7 | |
| SCHEMBL28818532 | 0.80 | P2RX7 (0.46) | KCNK3CREBBPBRD4P2RX7SCN9A | |
| SCHEMBL28818513 | 0.79 | KCNK3 (0.61) | KCNK3 | |
| SCHEMBL29844019 | 0.79 | KCNK3 (0.40) | KCNK3CREBBPBRD4SPTLC1P2RX7 | |
| SCHEMBL30044875 | 0.78 | P2RX7 (0.40) | KCNK3CREBBPBRD4SPTLC1P2RX7 | |
| SCHEMBL4830137 | 0.74 | KCNK3 (0.57) | KCNK3CREBBPBRD4SPTLC1TRPM2 | |
| SCHEMBL28818541 | 0.73 | MAPK1 (0.49) | CREBBPBRD4P2RX7 | |
| SCHEMBL19358387 | 0.72 | P2RX7 (0.48) | CREBBPSPTLC1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | disclosed |