SCHEMBL28818928

SCHEMBL28818928

COc1cccc(O)c1C.O[Si](O)(O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.59
MAPT P10636 2/20 0.59
KDM4E B2RXH2 1/20 0.59
ALDH1A1 P00352 1/20 0.59
LMNA P02545 1/20 0.59
CYP3A4 P08684 1/20 0.59
HPGD P15428 1/20 0.59
ALOX15 P16050 1/20 0.59
ALOX12 P18054 1/20 0.59
MAPK1 P28482 1/20 0.59
HSD17B10 Q99714 1/20 0.59
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
TSHR P16473 1/20 0.56
TRPA1 O75762 1/20 0.46
ATM Q13315 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CA12 O43570 2/20 0.42
CA7 P43166 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21288 0.94 MAPT (0.67) TP53MAPTKDM4EALDH1A1LMNA
SCHEMBL27637325 0.91 TP53 (0.64) TP53MAPTKDM4EALDH1A1LMNA
SCHEMBL11771708 0.77 LMNA (0.50) TP53MAPTKDM4EALDH1A1LMNA
SCHEMBL146841 0.77 CA1 (0.61) TP53MAPTKDM4EALDH1A1LMNA
3-Methoxycatechol SCHEMBL29477155 0.75 TP53 (1.00) TP53MAPTKDM4EALDH1A1LMNA
3-Methoxycatechol SCHEMBL67332 0.75 TP53 (1.00) TP53MAPTKDM4EALDH1A1LMNA
SCHEMBL28147356 0.74 TRPA1 (0.50) TP53MAPTKDM4EALDH1A1LMNA
Boric Acid SCHEMBL5237071 0.73 ENPP2 (0.54) TP53MAPTKDM4EALDH1A1LMNA
SCHEMBL70459 0.73 ESR1 (0.49) TP53MAPTKDM4EALDH1A1LMNA
SCHEMBL5624415 0.73 CA1 (0.50) TP53MAPTKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104725642-A Polymerized organic silicon flame-retardant charring agent polymer and preparation method thereof SUZHOU YANGQIAO CHEMICAL SCIENCE & TECHNOLOGY CO LTD 2015-06-24 CN disclosed