Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 14/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819256 | 0.92 | PKM (0.67) | GPR183PKMALDH1A1POLBLMNA | |
| SCHEMBL28819236 | 0.92 | GPR183 (0.62) | GPR183PKMALDH1A1POLBLMNA | |
| SCHEMBL28819260 | 0.91 | PKM (0.53) | GPR183PKMALDH1A1POLBLMNA | |
| SCHEMBL28819228 | 0.90 | PKM (0.53) | GPR183PKMALDH1A1POLBLMNA | |
| SCHEMBL28819261 | 0.86 | GPR183 (0.52) | GPR183PKMALDH1A1POLBLMNA | |
| SCHEMBL28819249 | 0.84 | ALDH1A1 (0.58) | GPR183PKMALDH1A1LMNA | |
| SCHEMBL28819254 | 0.84 | GPR183 (0.70) | GPR183PKMALDH1A1LMNA | |
| SCHEMBL28819240 | 0.82 | PKM (0.81) | GPR183PKMALDH1A1POLBLMNA | |
| SCHEMBL28819253 | 0.79 | LMNA (0.79) | GPR183PKMALDH1A1POLBLMNA | |
| SCHEMBL16598857 | 0.78 | GPR183 (1.00) | GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634465-B | Pentadienone derivative containing sulfonyl piperazine as well as preparation method and application thereof | 贵州大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-114634465-A | Sulfonyl piperazine-containing pentadiene ketone derivative and preparation method and application thereof | 贵州大学 | 2022-06-17 | — | — | CN | disclosed |